Tier 1: Chartered US banks
Mercury, Relay, Brex. Chartered US banks with FDIC partner coverage. Full integration with US payment systems (ACH, wire, Stripe, debit cards).
Pros: FDIC coverage, Treasury yield, mainstream payment processor integration, debit cards with spend controls. Cons: Lower approval rates for non-residents (50-70%), category restrictions (crypto exchanges, gambling, MSB all rejected).
Best for: SaaS, agency, e-commerce, services businesses where the country profile clears (~70%+ approval expected).
Tier 2: Money services providers
Wise Business, Payoneer, Airwallex. Money services (not chartered banks). Provide USD accounts with US routing and account numbers but custodial structure (no direct FDIC).
Pros: Broader acceptance (85-95%), multi-currency support, lower FX fees. Cons: No FDIC, no Treasury yield, may have feature limitations.
Best for: Fallback when Tier 1 rejects, international clients billing in EUR/GBP/AUD, marketplace payouts (Upwork, Fiverr, Amazon).
Tier 3: Crypto-friendly banks
Custodia Bank, BankProv. Specialized for digital asset businesses. Accept crypto exchanges, NFT marketplaces, and other crypto-native operations that Tier 1 banks reject.
Pros: Approve crypto businesses, support USDC and stablecoin operations. Cons: Higher fees, narrower features, smaller integration ecosystem.
Best for: Crypto exchanges, DeFi operators, NFT marketplaces, Web3 protocol operators.
How to sequence your applications
- If country profile is high-tier (UK, EU, Singapore): Mercury first, Relay second, Wise fallback.
- If country profile is mid-tier (India, UAE, Brazil): Mercury first, then Wise.
- If country profile is tightened (Pakistan, Nigeria, Vietnam): Wise first, Mercury stretch.
- If business is crypto-related: Wise primary, Custodia secondary. Mercury usually rejects.
- If revenue is $100K+/year: Add Brex to the stack.
Combined success rates
Across our 800-application intake, combined success rate (Mercury + Relay + Wise) is ~99%. Almost every non-resident founder ends up with at least one US-side banking option. The sequencing matters more than the individual bank choice.